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Harrison played in a playoff against other Americans to decide who would receive America's wildcard into the 2010 Australian Open. Harrison defeated Alex Kuznetsov and Donald Young in two sets, before defeating Jesse Levine in three straight sets. Once in the draw, Harrison lost in the first round to Janko Tipsarević in straight sets. At this point Harrison began competing in some bigger tournaments. First he received a wildcard into the 2010 SAP Open, where he lost to eventual semifinalist Denis Istomin in the first round. Next Harrison went through qualifying to face John Isner in the first round of the 2010 Regions Morgan Keegan Championships. Harrison lost in straight sets to the eventual finalist. Afterwards Harrison went through qualifying in the 2010 Delray Beach International Tennis Championships, before losing to eventual champion Ernests Gulbis in the first round. Harrison received a wildcard for the 2010 BNP Paribas Open, where he defeated Taylor Dent in the first round, before losing to the eventual winner Ivan Ljubičić. Having lost early, Harrison competed in the 2010 Sunrise Challenger where he lost first round, and then after receiving another wildcard into the 2010 Sony Ericsson Open lost in the first round to Michaël Llodra. Harrison played in a few challengers afterwards without any major results. On May 19, now ranked 263 in the world, Harrison entered the qualifying tournament for the 2010 French Open, after having lost in the final of the US Wildcard Playoff to Ryan Sweeting. Harrison lost in the final round of qualifying to Stefano Galvani. Harrison competed in the prestigious Queen's Championship with the likes of Murray, Djokovic, and Nadal, but would lose in the first round to Jesse Levine. Next Harrison would compete in Wimbledon Qualifying, but would lose in the first round to up and coming Lithuanian star Ričardas Berankis. Having not gained any points on his favourite surface, Harrison decided to compete in the 2010 Hall of Fame Tennis Championships. He defeated sixth seed Karol Beck 6-1, 6-2, before defeating seventeen year old Denis Kudla 7-5, 7-6(5). He then lost to Richard Bloomfield of Great Britain by a score of 5-7, 7-6(3), 7-5. Immediately after the tournament (as of July 12, 2010), he rose in the South African Airways ATP Rankings to a (young) career-high of #220.

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Tennis Forum